This was a systematic review of randomized controlled trials published from 1999 to 2008 to assess the evidence for a shorter mifepristone and misoprostol administration interval at first trimester medical termination. From Contraception.
The authors concluded that for late first-trimester termination, a single 800-mcg vaginal dose of misoprostol seems to be as effective as the mifepristone+misoprostol regimen, with acceptable side effects. From Contraception.
The study did not provide evidence that one mifepristone-induced abortion was associated with the risk of prolonged third stage of labour in a subsequent pregnancy in primiparae. From Paediatric and Perinatal Epidemiology.
The Hollywood actress Raquel Welch has blamed the widespread use of oral contraceptives for a breakdown in sexual morality, while others celebrate the liberating effects of safe and effective contraception.
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